Kunsthalle, Kahnweiler Saal, front entrance

13:30 - 17:00

WELCOME
Peter Hohenberger
Jean-Yves Blay

TUMOR VASCULARITY AND ANGIOGENESIS INHIBITORS
AS TARGETS IN SARCOMA

Chair : Pancras Hogendoorn, Leiden

• 13:30 – 14:00
  Alain Spatz (Paris)
  Pathobiological background of angiogenesis
• 14:00 – 14:30
  Peter Vajkoczy / Ralf Erber (Mannheim)
  Endothelial guidance molecules as mediators of tumor angiogenesis
• 14:30 – 15:00
  Stefan Sleijfer (Rotterdam)
  Targeting angiogenesis with vascular endothelial
  growth factor receptor small-molecule inhibitors

Coffee break

Chair: Ole S. Nielsen, Aarhus

• 15:30 – 16:00
  Martin Pruschy (Zurich)
  Combining ionizing radiation and inhibitors of angiogenesis
• 16:00 - 16:30
  Daniel Zips (Dresden)
  Combination of antiangiogenesis and radiotherapy:
  functional results in experimental tumors
• 16:30 – 17:00
  Ralf Kinscherf (Heidelberg)
  Effects of anti-angiogenic gene transfer in hepatoma

17:00 - 18:30

Special Symposium
CONTICA.NET , EuroBoNET and EORTC-STBSG:

POTENT NETWORKS AND POTENTIAL BACKBONE
OF COORDINATED RESEARCH FOR SARCOMA IN EUROPE

Speakers:

• Jean-Yves Blay, Lyon
  CONTICA.NET: General overview
  
• Working packages
  Ricardo Rossi, Padova
  Patrick Schöffski, Leuven
  Michael. Scurr, London
  Paolo Casali, Milano
• Pancras Hogendoorn, Leiden
  Structure of EuroBoNET
• Martine van Glabekke, Brussels
  EORTC STBSG - Network Organizing Cancer Research

19:00 - 21:30

WELCOME RECEPTION

Kunsthalle, Heinrich Vetter Forum
Music by Trio Ivoire

08.30 – 12.00

CURRENT STANDARDS OF TREATMENT OF GI STROMAL TUMORS

Chair : Jaap Verweij, Rotterdam

Speakers:

• 8:30 – 9:00
  Ian Judson (London)
  Current trials and new agents for GIST
• 9:00 – 9:30
  Andreas Hochhaus (Mannheim)
  Bridging from CML to GIST
• 9:30 – 9:45
  Antonia Dimitrakopoulou-Strauss (Heidelberg)
  New targets to image GI stromal tumors

Coffee Break

Chair : Peter Reichardt, Berlin

• 10:15 - 10.35
  Martine van Glabekke (Brussels)
  Predicting toxicity of imatinib treatment - data from EORTC 62005
• 10:35 – 10:55
  Axel LeCesne (Paris)
  A critical analysis of the impact of RECIST criteria in 62005 trial
• 10:55 – 11:10
  Piotr Rutkowski (Warszaw)
  Outcomes and prognostic factors for overall survival of patients with metastatic/inoperable gastrointestinal stromal tumor (GIST) treated with imatinib - a report of Polish Clinical GIST Registry
• 11:10 – 11:45
  Peter Hohenberger / Binh Bui (Mannheim / Bordeaux, FSG)
  Indication and results for surgery following treatment mit Imatinib mesylate in advanced GIST

12:00 – 13:00

LUNCH

13:00– 16:00

DIAGNOSTIC TOOLS TO SELECT PATIENTS AND
MONITOR TREATMENT FOR TARGETED THERAPY

Chair : Margaret Ashcroft, London

Speakers:

• 13:00 – 13:45
  Bruno Domon (Zurich)
  Quantitative proteomics for biomarker discovery and evaluation
• 13:45 – 14:00
  J.Y.Blay, P. Schöffski,
  A. LeCesne,
  KK Sankhala,
  S.T. Daly,
  A. Tolcher,
  S.P. Chawla,
  G.D. Demetri
  for the AP23573 Sarcoma Study Group
  Updated interim phase II results of AP23573, a novel mTOR inhibitor,
  in patients with advanced soft tissue of bone sarcoma
• 14:00 – 14:45
  Margaret Ashcroft (London)
  Tumor angiogenesis driven by hypoxia
• 14:45 – 15:15
  Peter Wust (Berlin)
  Noninvasive MR monitoring of temperature and perfusion during regional hyperthermia in soft tissue sarcoma
• 15:15- 15:30
  Bernd Kasper (Brussels/Heidelberg)
  Prediction of therapy outcome using FDG PET

19:30

GROUP DINNER EORTC STBSG
(registered participants only)

At the ONYX

Saturday April 8, 2006


08:30 - 9:30

Subgroup meetings STBSG

• Local Treatment Group Kunsthalle, Library (rear entrance)
• Systemic Treatment Group Kunsthalle, Clubroom (main entrance, 1st floor)
• Pathology and Translational Research Group

09:30 – 10:30

Business Meeting STBSG
- Full Members only -
Kunsthalle, Clubroom (main entrance, 1st floor)

Coffee Break

11:00 – 14:00

General Meeting STBSG
- TRIAL STATUS REPORT -
Kunsthalle, Clubroom (main entrance, 1st floor)

Separate agenda available

14:00

Adjourn

Friday, April 7, 16:00 Library

Meeting of the German Interdisciplinary Working Party on Sarcoma (IWS)

J.T.Hartmann

Saturday, April 8, 14:30 Library

Advisory Board Meeting, Pfizer Germany